The Detroit Red Wings face off against the Buffalo Sabres on Wednesday, October 22, 2025, at 7:30 p.m. ET at KeyBank Center. The game will be broadcast in the U.S. on TNT and available for streaming on HBO Max and FuboTV (regional restrictions may apply). Canadian viewers can catch the action on Sportsnet.
The Detroit Red Wings (5-1-0) enter this matchup riding a five-game win streak, including a recent 4-2 victory over the Edmonton Oilers. Led by captain Dylan Larkin (5 goals, 6 assists), Detroit has surged to the top of the Atlantic Division. Supporting Larkin are Alex DeBrincat (6 assists) and Lucas Raymond, both contributing to a potent offense.
Buffalo Sabres (2-4-0) are looking to bounce back after a 4-2 loss to the Montreal Canadiens. Their top performers include Zach Benson (6 points), Jason Zucker (3 goals), and Tage Thompson (3 points). Despite a rocky start, Buffalo has shown flashes of offensive firepower, notably in their 8-4 win over Ottawa earlier this season.
The betting line favors Detroit at -115, with an Over/Under set at 5.5 goals. Given Detroit’s momentum and Buffalo’s defensive struggles, our prediction is a 4-2 win for the Red Wings. Expect Larkin and Raymond to capitalize on Buffalo’s penalty kill, while Sabres fans hope for a breakout night from Thompson.
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